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Self-Powered Blood Coagulation Chip For Inr Value And Hematocrit Determination


Project TitleSelf-Powered Blood Coagulation Chip For Inr Value And Hematocrit Determination
Track Code22146
Short DescriptionNone
AbstractWith the increased use of anticoagulant drugs comes a greater risk of life threatening side effects. Patient monitoring of blood coagulation levels can help curb these adverse side effect. Unfortunately, this practice is not widely used today due to the relatively high cost of personal coagulation monitors.

Researchers at the University of California, Berkeley have developed a low cost, point-of-test diagnostic chip to simultaneously determine blood coagulation time (INR Value) and hematocrit level – two indicators that can help determine if the correct dosage of anticoagulant medication is being taken. The chip is intended to be a simple, disposable device that can be cheaply mass fabricated using hot embossing or injection molding techniques. A finger prick volume of blood is placed at the inlet of the device and self-powered method within the device is used to drive the flow of whole blood. Both aspects of the device (lNR and Hematocrit) are novel.
Posted DateJun 1, 2017 7:21 AM


  • Easily and cheaply mass produced
  • Is self-powered and disposable
  • Readout is indicated by designations on the platform with the inputted blood acting as the readout mechanism.
  • Beneficial to physicians in the developing world and resource-limited areas.

Potential Applications

  • Self-management tool for people with chronic bleeding disorders or those who use oral anticoagulants as a long-term prophylaxis.
  • Monitors hematocrit level, which is indicative of the No. 1 side effect and cause of death of anticoagulants - hemorrhage. Current self-monitoring devices do not have the capability.

Additional Information

Contact Information

Name : Curt Theisen

Title :

Department :

Email :

Phone : 510-643-7214

Address :

Principal Investigator

Name : Ivan Dimov

Department :

Name : Luke Lee

Department :

Name : Benjamin Ross

Department :

Name : John Waldeisen

Department :

Intellectual Property

Patent Number : 20150233894

Patent Title :

Patent Application Date :

Patent Publication Date :

Patent Issue Date : Aug 20, 2015

Patent Link :