Pathogen Resistance In Plants Using Cdna-n/intron Constructs

Organization Name	University of California, Berkeley (UC Berkeley)
Institutional ID Number	18570
Technology Tags or Keywords	pesticides plant resistance Transgenics
Summary	N genes were shown to require partial alternative processing of the third intron, which produces a truncated N protein, to provide full viral resistance. Insertion of a complete cDNA or truncated construct alone did not provide resistance in transgenic plants. Researchers at UC Berkeley have developed constructs comprising (1) a cDNA molecule corresponding to the tobacco N gene, and (2) at least a portion of the third intron of the N gene. Transgenic plants with this construct result in the required, partial, alternative processing to result in virus resistance.
Technology Benefit	Use native plant gene sequences to provide TMV resistance in other crop species.
Technology Applications	Generation of TMV resistant plants.
Technology page URL	http://techtransfer.universityofcalifornia.edu/NCD/18570.html?utm_source=AUTMGTP&utm_medium=webpage&utm_term=ncdid_18570&utm_campaign=TechWebsites
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Additional Information	Related Technologies Compositions And Methods For Plant Pathogen Resistance Tech ID/UC Case 18570/1998-062-0 Related Cases 1998-062-0