|Organization Name||Wisconsin Alumni Research Foundation (WARF)|
|Institutional ID Number||P06053US|
|Technology Tags or Keywords|
The Wisconsin Alumni Research Foundation (WARF) is seeking commercial partners interested in developing methods and compositions for controlling serum phosphate levels in mammals.
|Technology page URL||http://www.warf.org/technologies.jsp?ipnumber=P06053US|
|Detailed Technology Description||
The kidney filters toxins and excess nutrients from the blood. It also synthesizes the active form of vitamin D3. In patients with chronic kidney disease, levels of active vitamin D3 decline, leading to hypocalcemia. At the same time, nutrients, particularly phosphorous, accumulate in the blood. Hypocalcemia and excess phosphorous stimulate the secretion of parathyroid hormone (PTH). PTH can cause excess bone resorption, leading to a condition known as renal osteodystrophy.
|TTO homepage URL||http://www.warf.org|
|URL to link to documents, images, videos, etc.||--|