A Method of Dynamically Conforming Predefined Photon Beams to a Tumor Volume
Organization: STC UNM
Due to the computational complexity there is no high-quality automated treatment planning system for Gamma Knife radiosurgery, and Gamma Knife treatments are primarily planned by humans through trial-and-error. We have disentangled the various engineering and computational problems and developed a new Gamma Knife radiosurgery scheme by bringing together techniques from computational geometry, algorithms, and operations research. Our invention will allow physicians to obtain Gamma Knife radiosurgery plans and treatments that will ...
Organization: STC UNM
This technology includes non-invasive diagnostic agents for cancer and methods for diagnosing cancer, especially leukemia and lymphoma. Additionally, these novel compounds may be used for treating and preventing cancers, especially leukemia and lymphoma. The technology includes a small molecule that binds to LFA-1 (CD18, CD11a)1, a integrin cell surface receptor specifically expressed on leukocytes, lymphoma and leukemia cells. The limited expression of LFA-1 on normal white blood cells versus significant overexpression on ...
Peptide Radiopharmaceuticals for Melanoma Detection and Therapy
Organization: STC UNM
The present invention is a novel use of a melanoma-specific [labeled, lactam bridge-cyclized alpha-melanocyte stimulating hormone] peptide to target melanocortin-1 (MC1) receptors to improve the early and accurate detection of melanoma.
Novel Hybrid Peptide for Imaging and Treatment of Melanoma
Organization: STC UNM
The present technology describes novel non-invasive diagnostic tools/compounds which can be used to image and treat melanoma. The radio-labeled peptide probes can specifically bind to the melanocyte simulating hormone (MSH) receptors that are over-expressed on melanoma cells. Upon binding to the receptor they can be rapidly internalized and selectively deliver diagnostic or therapeutic radionuclides to melanoma tumor cells for imaging or therapy. This means that these probes can not only be used as an effective diagnostic agent ...
